The SPLITMUX-HD-4RT and SPLITMUX-C5HDR-4LC can be cascaded together in any combination, with either model as the master and/or slaves in any combination and any number of slave levels. The SPLITMUX-HD-4RT supports Full Screen, PiP, Quad, and Custom modes. The SPLITMUX-C5HDR-4LC supports Full Screen PiP, and Quad modes. Keep both limitations in mind when configuring the desired cascade effect. Cascaded outputs for the SPLITMUX-C5HDR-4LC can be extended using the remote unit as long as the combined CAT6/6a/7 cable length between all levels of the cascade does not exceed 250 feet.
In this example, the SPLITMUX-HD-4RT is the master unit, and the four slaves are SPLITMUX-C5HDR-4LC units. Slave 1 and 2 are configured as Full Screen mode, Slave 3 as PiP mode, and Slave 4 as Quad mode.  Input/Slave 1 is also extended up to 250 feet using a single CAT6/6a/7 cable. Using Custom Mode on the master unit, the following inputs are configured as below:
Input/Slave 1:
  - Background image
  - Red border
Input/Slave 2:
  - Vertical image using adjusted aspect ratio
  - Blue border
Input/Slave 3:
  - Windowed image (Quad image)
  - Green border
Input/Slave 4:
  - Overlapping windowed image (PiP image)
  - Yellow border
Note: SPLITMUX-C5HDR-4LC is not TAA or HDCP compliant.
Below are the configuration limitations for a cascade set-up
| Master | Slaves | How to Configure | 
| SPLITMUX-HD-4RT | SPLITMUX-C5HDR-4LC | Individually | 
| SPLITMUX-C5HDR-4LC | SPLITMUX-HD-4RT | Individually | 
| SPLITMUX-HD-4RT | SPLITMUX-HD-4RT, SPLITMUX-C5HDR-4LC
 | All connected SPLITMUX-HD-4RT can be adjusted via the master's Custom Mode in Web Interface as long as there is a chain link; all connected SPLITMUX-C5HDR-4LC must be configured individually | 
| SPLITMUX-C5HDR-4LC | SPLITMUX-HD-4RT, SPLITMUX-C5HDR-4LC
 | Individually |